The association between low birth weight and mothers diseases in Iran: A case-control study

Valadbeigi, T., Tabatabaee, H.R, Etemad, K, Keyghobadi, N., Mahdavi, S., Enayatrad, M., Saeidinejat, S., Yaghoobi, H., Zolfizadeh, F., Ghasemi, A., Hajipour, M.* | JNPM 2020;

BACKGROUND: Neonates are too vulnerable that low birth weight (LBW) and preterm birth can easily threaten their lives. Demographic, social and environmental factors as well as health care are contributing factors for LBW. The study was conducted in 10 provinces of Iran to investigate the association between LBW and mother’s diseases.
METHODS: A case-control study was conducted in 10 provinces of Iran on 2580 mothers (712 cases and 1868 controls) referred to public health care centers. We used a questionnaire to collect data. For univariate analysis we used chi-square test and for multivariable analysis we used logistic regression model.
RESULTS: LBW was significantly associated with living in rural area (OR = 1.4 CI: 1.14–1.71), having body mass index (BMI)<18 (OR = 1.48 CI: 1.14–1.92), being a housewife (OR = 1.65 CI: 1.07–2.53), having high blood pressure (OR = 1.91 CI: 1.26–2.88), and having pregnancy without testing for diabetes (OR = 1.91 CI: 1.44–2.54). Minor thalassemia, hypothyroidism, oral health care and headache were not significant predictors for LBW.
CONCLUSION: In this study, we observed that place of residence, BMI before pregnancy, mother’s occupation and gestational diabetes were significant predictors of LBW. It is necessary to improve women’s awareness about prenatal health care before pregnancy to avoid LBW.

*Corresponding Author: 

Mahmoud Hajipour, Student research committee, Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Tel.: +98 7137251001; E-mail: