Abstract: OBJECTIVES: Analogous to the Near Miss Maternal approach, the concept of Near Miss Neonatal (NNM) is an approach recently developed to identify newborns who survive near-fatal complications during the first 28 days of ectopic life. The objective of this study is to shed light on the cases of Neonatal Near Miss and identify its factors associated with live births. METHODS: A prospective cross-sectional study was conducted to identify factors associated with Neonatal Near Miss in newborns admitted to the National Reference Center in Neonatology in Rabat, Morocco from January 1 to December 31, 2021. A pre-tested, structured questionnaire was used to collect the data. These data were entered using Epi Data software and exported to SPPS23 for analysis. To identify the determinants of the outcome variable, binary multivariable logistic regression was used. RESULTS: Among the 2676 selected live births, 2367 (88.5%; 95% CI: 88.3–90.7)) were cases of NNM. Factors in women which were significant predictors of NNM included being referred from other health care facilities [AOR: 1.86; 95% CI: 1.39–2.50], residing in a rural area [AOR: 2.37; 95% CI: 1.82–3.10], having less than four prenatal visits [AOR: 3.17; 95% CI: 2.06–4.86], and having gestational hypertension [AOR: 2.02; 95% CI: 1.24–3.30]. CONCLUSIONS: This study revealed a high proportion of NNM cases in the study area. The factors associated with NNM which were found to increase these cases demonstrates the primary health care program must be further improved to avoid preventable causes of neonatal mortality.